Please use this identifier to cite or link to this item: http://mfuir.mfu.ac.th:80/xmlui/handle/123456789/565
Title: Daldinia eschscholtzii (Ehrenb.: Fr) Rehm, a new record in West Bengal and its mycochemistry, antioxidant contents and activity, lipoxygenase inhibitory activity and molecular docking of its prevalent compound, phloretin, with reactive oxygen species (ROS
Authors: Bera T,
Ghosh SK,
Chatterjee R.
Keywords: Antioxidant Content;Activity;LC-MS;Lipoxygenase inhibition;Molecular Docking;Phloretin
Issue Date: 30-May-2024
Publisher: Center of Excellence in Fungal Research, Mae Fah Luang University
Citation: Asian Journal of Mycology (AJOM). Vol.8, No.1 (January - June 2025): p.57-85
Abstract: Daldinia eschscholtzii, collected from West Bengal, India, was evaluated for its antioxidant content and activity, as well as its lipoxygenase inhibitory potential from the ethanolic extract. Bioactive compounds were identified using LC-MS, followed by molecular docking between selected compounds and enzymes (lipoxygenase, xanthine oxidase, and CYP1A1). Results indicated significant levels of total phenolic content, total flavonoid content, and total antioxidant activity. LC-MS analysis of DEE (Daldinia ethanolic extract) detected 28 compounds in the extract. Molecular docking studies revealed a high binding affinity of phloretin with ROS-producing enzymes, suggesting potential enzyme inhibition. In conclusion, Daldinia eschscholtzii is revealed as a good source of antioxidant, anti-cancerous and LOX-inhibiting compounds.
Description: บทความ (Article)
URI: http://mfuir.mfu.ac.th:80/xmlui/handle/123456789/565
ISSN: 2651-1339
Appears in Collections:บทความ (Article)

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